Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.32 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | PDE1A | P54750 | 1/20 | 0.30 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28987256 | 0.93 | OPRK1 (0.36) | HSD17B10DYRK1AOPRK1HRH4 | |
| SCHEMBL25389131 | 0.76 | RXRA (0.43) | OPRK1KMT2A | |
| SCHEMBL31104405 | 0.74 | KMO (0.43) | PIK3CD | |
| SCHEMBL16595822 | 0.74 | KMO (0.43) | PIK3CD | |
| SCHEMBL27402945 | 0.74 | HDAC8 (0.38) | HSD17B10PIK3CDOPRK1HTR3AKCNH2 | |
| SCHEMBL30853275 | 0.74 | HDAC8 (0.38) | HSD17B10PIK3CDOPRK1HTR3AKCNH2 | |
| SCHEMBL16302863 | 0.73 | HSD17B10 (0.39) | HSD17B10DYRK1AHTTKMT2A | |
| SCHEMBL16913940 | 0.72 | PIK3C3 (0.49) | HSD17B10DYRK1A | |
| SCHEMBL15333094 | 0.72 | HSD17B10 (0.46) | HSD17B10DYRK1AHRH4HTTKMT2A | |
| SCHEMBL29377303 | 0.72 | HSD17B10 (0.46) | HSD17B10DYRK1AHRH4HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003408-A | Heterocyclic compound, and preparation method and application thereof | 绵阳市中心医院 | 2023-04-25 | — | — | CN | disclosed |