Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 13/20 | 0.36 |
| ▸ | PDE9A | O76083 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28987252 | 0.93 | HSD17B10 (0.35) | OPRK1HRH4HSD17B10DYRK1A | |
| SCHEMBL25389131 | 0.79 | RXRA (0.43) | OPRK1 | |
| SCHEMBL2980987 | 0.75 | PIK3CD (0.41) | PDE9A | |
| SCHEMBL19698021 | 0.74 | PIK3CD (0.41) | PDE9A | |
| SCHEMBL19966455 | 0.74 | KDM5A (0.47) | PDE9A | |
| SCHEMBL17677989 | 0.72 | PIK3CD (0.41) | PDE9A | |
| SCHEMBL25045382 | 0.72 | HTR7 (0.39) | PDE9AHCAR3 | |
| SCHEMBL10124057 | 0.72 | ALDH1A1 (0.40) | OPRK1PDE9AHSD17B10HCAR3 | |
| SCHEMBL24268689 | 0.71 | HCAR3 (0.42) | PDE9AHSD17B10HCAR3 | |
| SCHEMBL24268646 | 0.71 | NR3C1 (0.39) | PDE9AHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003408-A | Heterocyclic compound, and preparation method and application thereof | 绵阳市中心医院 | 2023-04-25 | — | — | CN | disclosed |