Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPYD | Q12882 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7884 | 1.00 | — | — | |
| 5-Bromouracil SCHEMBL8224638 | 0.87 | DPYD (0.76) | DPYDMAPTALDH1A1GAALMNA | |
| SCHEMBL7250168 | 0.87 | DPYD (0.76) | DPYDMAPTALDH1A1GAALMNA | |
| SCHEMBL14793573 | 0.81 | DPYD (0.66) | DPYDMAPTALDH1A1GAALMNA | |
| Hypoxanthine SCHEMBL22323646 | 0.80 | DPYD (0.63) | DPYDMAPTALDH1A1GAALMNA | |
| SCHEMBL5801644 | 0.72 | ALDH1A1 (0.64) | DPYDMAPTALDH1A1GAALMNA | |
| SCHEMBL6573722 | 0.70 | — | — | |
| SCHEMBL7177835 | 0.69 | DPYD (0.52) | DPYDMAPTALDH1A1GAALMNA | |
| SCHEMBL6555485 | 0.69 | DPYD (0.52) | DPYDMAPTALDH1A1GAALMNA | |
| Thymine SCHEMBL15323914 | 0.68 | ATAD2 (1.00) | DPYDMAPTALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428201-A1 | Oral administration of nucleoside monophosphates | Merck Serono S.A. (CH) | 2012-03-14 | — | — | EP | disclosed |