Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907652 | 0.69 | TDP1 (0.37) | ALOX15TSHR | |
| SCHEMBL6747253 | 0.69 | EPHX1 (0.36) | TSHRLMNACYP3A4GABRA1GABRG2 | |
| SCHEMBL26694 | 0.69 | GABRA5 (0.39) | ALOX15TSHRLMNACYP3A4GABRA1 | |
| SCHEMBL6535865 | 0.69 | TSHR (0.47) | ALOX15TSHRLMNACYP3A4GABRA1 | |
| SCHEMBL454712 | 0.68 | — | — | |
| SCHEMBL27527086 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL27741891 | 0.67 | ALOX15 (0.46) | ALOX15TSHRGABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL1902054 | 0.67 | GABRA5 (0.38) | ALOX15TSHRLMNACYP3A4GABRA1 | |
| SCHEMBL7138787 | 0.67 | GBA1 (0.38) | ALOX15TSHRGABRA1GABRG2GABRB3 | |
| Hydrochloric Acid SCHEMBL23199282 | 0.66 | GABRA5 (0.40) | ALOX15TSHRLMNACYP3A4GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996912-A | Iminothiolanone inhibitors of ENPP1 | 沃拉斯查疗法公司 | 2023-04-21 | — | — | CN | disclosed |