Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535865 | 0.73 | TSHR (0.47) | GNAO1GNAI3GNAI1ALOX15TSHR | |
| SCHEMBL27527086 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL27741891 | 0.71 | ALOX15 (0.46) | TDP1GNAO1GNAI3GNAI1ALOX15 | |
| SCHEMBL7138787 | 0.71 | GBA1 (0.38) | TDP1GNAO1GNAI3GNAI1ALOX15 | |
| SCHEMBL28987464 | 0.69 | ALOX15 (0.34) | ALOX15TSHR | |
| SCHEMBL14077938 | 0.68 | CHRM2 (0.37) | — | |
| SCHEMBL25610380 | 0.68 | NOS2 (0.35) | TDP1GNAO1GNAI3GNAI1ALOX15 | |
| SCHEMBL10154182 | 0.68 | NOS2 (0.35) | TDP1GNAO1GNAI3GNAI1ALOX15 | |
| SCHEMBL27363514 | 0.68 | GNAO1 (0.36) | TDP1GNAO1GNAI3GNAI1ALOX15 | |
| SCHEMBL24822647 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661148-A | ANTIHYPOXIC AGENT FOR RESPIRATORY SYSTEM DISORDER | TEIJIN LIMITED (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0514540-B1 | PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 1996-07-17 | — | — | EP | disclosed |
| EP-0514540-A1 | PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1992-11-25 | — | — | EP | disclosed |