SCHEMBL28987486

SCHEMBL28987486

CC(CO)c1ccc(O)c(O)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 3/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
TSHR P16473 2/20 0.38
ADRA2A P08913 2/20 0.37
ADRA2B P18089 2/20 0.37
ADRA2C P18825 2/20 0.37
ADRA1A P35348 2/20 0.37
ADRA1B P35368 1/20 0.37
ACE2 Q9BYF1 2/20 0.36
RORC P51449 1/20 0.35
RNASEH1 O60930 1/20 0.34
FAAH O00519 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
GABRA1 P14867 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2382143 0.83 TSHR (0.57) ADRB2ADRB1ADRB3TSHRADRA2A
SCHEMBL28269343 0.78 GABRA1 (0.39) ADRB2ADRB1ADRB3TSHRADRA2A
SCHEMBL487169 0.77 GABRA1 (0.56) ADRB2ADRB1ADRB3TSHRADRA2A
SCHEMBL9614891 0.77 ADRB2 (0.39) ADRB2ADRB1ADRB3TSHRADRA2A
SCHEMBL24217828 0.75 ADRB2 (0.42) ADRB2ADRB1ADRB3TSHRADRA2A
SCHEMBL2989000 0.75 ADRB2 (0.42) ADRB2ADRB1ADRB3TSHRADRA2A
SCHEMBL30046916 0.75 ADRB2 (0.42) ADRB2ADRB1ADRB3TSHRADRA2A
SCHEMBL5561577 0.74 ADRA2A (0.41) ADRB2ADRB1ADRB3ADRA2AADRA2B
SCHEMBL2976451 0.74 ADRB2 (0.46) ADRB2ADRB1ADRB3TSHRADRA2A
SCHEMBL7716595 0.74 IAPP (0.40) ADRB2ADRB1ADRB3ADRA2AADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115843302-A Thermoplastic polyurethane compositions comprising nitro-substituted polyester diols 诺弗洛普有限公司 2023-03-24 CN disclosed
CN-115843300-A Polymerizable compositions comprising nitro-substituted polyester diols 诺弗洛普有限公司 2023-03-24 CN disclosed