Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990326 | 0.80 | PGR (0.48) | PGRPRKDCMAPTPTPN1PTPN2 | |
| SCHEMBL28590304 | 0.80 | PTPN1 (0.59) | PGRMAPTPTPN1PTPN2SMN1; SMN2 | |
| SCHEMBL28586119 | 0.78 | PTPN1 (0.42) | MAPTPTPN1PTPN2SMN1; SMN2MEN1 | |
| SCHEMBL30367335 | 0.77 | PGR (0.46) | PGRMAPTPTPN1PTPN2SMN1; SMN2 | |
| SCHEMBL28988631 | 0.77 | PGR (0.46) | PGRMAPTPTPN1PTPN2SMN1; SMN2 | |
| SCHEMBL28596598 | 0.77 | PTPN1 (0.46) | PTPN1PTPN2USP2ALDH1A1 | |
| SCHEMBL28586498 | 0.76 | PTPN1 (0.46) | MAPTPTPN1PTPN2KDM4EUSP2 | |
| SCHEMBL28596566 | 0.74 | MAOA (0.48) | MAPTPTPN1PTPN2SMN1; SMN2KDM4E | |
| SCHEMBL25442219 | 0.72 | PTPN1 (0.56) | PTPN1KDM4EMEN1HTTKMT2A | |
| SCHEMBL18878405 | 0.72 | PTPN1 (0.56) | MAPTPTPN1SMN1; SMN2MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974825-B | Method for preparing 3-substituted chromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2024-03-05 | — | — | CN | disclosed |
| CN-115974825-A | Method for preparing 3-substituted chromanone through metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2023-04-18 | — | — | CN | disclosed |