Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | PRKDC | P78527 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28988633 | 0.80 | PGR (0.45) | PGRPRKDCPTPN1PTPN2MAPT | |
| SCHEMBL28990301 | 0.78 | PTPN1 (0.64) | PGRPRKDCPTPN1PTPN2KDM4E | |
| SCHEMBL28990305 | 0.74 | PGR (0.48) | PGRPTPN1PTPN2KDM4EUSP2 | |
| SCHEMBL28990316 | 0.72 | PTPN1 (0.65) | PTPN1KDM4EMEN1GAAHTT | |
| SCHEMBL4933924 | 0.71 | KCNH2 (0.50) | PGRPRKDCKCNH2SLC6A11ERN1 | |
| SCHEMBL29116198 | 0.69 | ALDH1A1 (0.55) | PTPN1MAPTUSP2GAAMAOB | |
| SCHEMBL28990318 | 0.69 | PTPN1 (0.61) | PTPN1MAPTKDM4EMEN1POLB | |
| SCHEMBL28990323 | 0.69 | PTPN1 (0.61) | PTPN1POLBKMT2AKCNH2MAOB | |
| SCHEMBL23954203 | 0.68 | KCNH2 (0.47) | PGRPRKDCMAPTKDM4EKCNH2 | |
| SCHEMBL6318301 | 0.68 | KCNH2 (0.55) | PGRMAPTKDM4EKCNH2SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991695-B | Method for preparing 3-fluorochromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2024-06-21 | — | — | CN | disclosed |
| CN-115991695-A | Method for preparing 3-fluorochromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2023-04-21 | — | — | CN | disclosed |