Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28988631 | 1.00 | PGR (0.46) | PGRPTPN1PTPN2ALDH1A1USP2 | |
| SCHEMBL28590304 | 0.83 | PTPN1 (0.59) | PGRPTPN1PTPN2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28596598 | 0.80 | PTPN1 (0.46) | PTPN1PTPN2ALDH1A1USP2TSHR | |
| SCHEMBL28990305 | 0.80 | PGR (0.48) | PGRPTPN1PTPN2ALDH1A1USP2 | |
| SCHEMBL28586498 | 0.80 | PTPN1 (0.46) | PTPN1PTPN2ALDH1A1USP2TSHR | |
| SCHEMBL28988633 | 0.77 | PGR (0.45) | PGRPTPN1PTPN2ALDH1A1USP2 | |
| SCHEMBL28596566 | 0.77 | MAOA (0.48) | PTPN1PTPN2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28586119 | 0.76 | PTPN1 (0.42) | PTPN1PTPN2ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25442219 | 0.75 | PTPN1 (0.56) | PTPN1KDM4EMEN1KMT2A | |
| SCHEMBL18878405 | 0.75 | PTPN1 (0.56) | PTPN1ALDH1A1SMN1; SMN2PIM1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974825-A | Method for preparing 3-substituted chromanone through metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2023-04-18 | — | — | CN | disclosed |