Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.34 |
| ▸ | GGT1 | P19440 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989735 | 0.84 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDL3MBTL1GFER | |
| SCHEMBL28988942 | 0.74 | KDM4E (0.47) | ALDH1A1HSD17B10KDM4EHPGDL3MBTL1 | |
| SCHEMBL28988944 | 0.74 | ALDH1A1 (0.36) | ALDH1A1HSD17B10KDM4EHPGDL3MBTL1 | |
| SCHEMBL30396310 | 0.73 | HSD17B10 (0.47) | ALDH1A1HSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL28988936 | 0.73 | HSD17B10 (0.47) | ALDH1A1HSD17B10KDM4EHPGDKMT2A | |
| SCHEMBL16719162 | 0.71 | KDM4E (0.71) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL8667165 | 0.67 | KDM4E (0.79) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL1358288 | 0.67 | KDM4E (0.63) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL16248157 | 0.67 | KDM4E (0.59) | ALDH1A1HSD17B10KDM4EHPGDMAPK1 | |
| SCHEMBL30396306 | 0.66 | KMT2A (0.52) | ALDH1A1L3MBTL1KMT2ATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613744-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Guangdong Zhongke Medicine Research Ltd. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-115991698-B | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115991698-A | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2023-04-21 | — | — | CN | disclosed |