Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 2/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28989735 | 0.81 | ALDH1A1 (0.43) | KDM4EMYCALDH1A1L3MBTL1MAPT | |
| SCHEMBL28988944 | 0.76 | ALDH1A1 (0.36) | KDM4ETDP1KDM5AKDM4CKDM5B | |
| SCHEMBL28988946 | 0.74 | ALDH1A1 (0.45) | KDM4ETDP1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL270419 | 0.67 | KDM4E (1.00) | KDM4ETDP1MYCKDM4CALDH1A1 | |
| SCHEMBL30639802 | 0.66 | KDM4E (0.95) | KDM4ETDP1MYCKDM4CALDH1A1 | |
| SCHEMBL30639818 | 0.66 | KDM4E (0.95) | KDM4ETDP1MYCKDM4CALDH1A1 | |
| SCHEMBL29723448 | 0.66 | KDM4E (0.95) | KDM4ETDP1MYCKDM4CALDH1A1 | |
| SCHEMBL29669957 | 0.66 | KDM4E (0.61) | KDM4ETDP1MYCALDH1A1L3MBTL1 | |
| SCHEMBL7032479 | 0.65 | KDM4E (0.78) | KDM4ETDP1MYCALDH1A1L3MBTL1 | |
| SCHEMBL31681889 | 0.65 | LMNA (0.38) | KDM4ETDP1ALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991698-B | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-115991698-A | Heterocyclic compound and preparation method and application thereof | 广东中科药物研究有限公司 | 2023-04-21 | — | — | CN | disclosed |