SCHEMBL289898

SCHEMBL289898

CC(C(=S)S)c1ccccn1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.56
CYP3A4 P08684 2/20 0.56
ALDH1A1 P00352 2/20 0.42
SLC6A3 Q01959 2/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42
TSHR P16473 2/20 0.42
KCNA5 P22460 6/20 0.40
KCNH2 Q12809 1/20 0.40
KDM4E B2RXH2 4/20 0.39
MAPT P10636 1/20 0.38
CYP2C19 P33261 1/20 0.38
KCNE1 P15382 2/20 0.38
CYP2D6 P10635 1/20 0.38
LMNA P02545 2/20 0.37
ABCB11 O95342 1/20 0.37
ESR1 P03372 1/20 0.37
ADRA2A P08913 1/20 0.37
CYP2C9 P11712 1/20 0.37
PDE4A P27815 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6256359 0.86 CYP1A2 (0.56) CYP1A2CYP3A4ALDH1A1SLC6A3SLC6A2
SCHEMBL4389588 0.82 CYP1A2 (0.53) CYP1A2CYP3A4ALDH1A1SLC6A3SLC6A2
SCHEMBL11832284 0.81 CYP1A2 (0.51) CYP1A2CYP3A4ALDH1A1SLC6A3SLC6A2
SCHEMBL4389584 0.81 CYP3A4 (0.60) CYP1A2CYP3A4ALDH1A1SLC6A3SLC6A2
Hydrochloric Acid SCHEMBL11193599 0.79 CYP1A2 (0.50) CYP1A2CYP3A4ALDH1A1SLC6A3SLC6A2
SCHEMBL11195298 0.78 CYP1A2 (0.49) CYP1A2CYP3A4ALDH1A1SLC6A3SLC6A2
SCHEMBL18601246 0.77 KCNA5 (0.44) CYP1A2CYP3A4ALDH1A1SLC6A3SLC6A2
SCHEMBL27536605 0.76 CYP1A2 (0.64) CYP1A2CYP3A4ALDH1A1SLC6A3SLC6A2
SCHEMBL289900 0.75 CYP1A2 (0.53) CYP1A2CYP3A4ALDH1A1SLC6A3SLC6A2
SCHEMBL24239786 0.74 CYP3A4 (0.53) CYP1A2CYP3A4ALDH1A1SLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12569439-B2 Bottom-up assembly of synthetic extracellular vesicles MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2026-03-10 US claimed
EP-4684872-A1 DEVICE AND METHOD FOR WATER-IN-AIR GENERATION OF DROPLETS Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2026-01-28 EP claimed
US-20230181466-A1 BOTTOM-UP ASSEMBLY OF SYNTHETIC EXTRACELLULAR VESICLES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-06-15 US claimed
EP-4164693-A1 NANOLIPOPROTEIN-POLYPEPTIDE CONJUGATES AND COMPOSITIONS, SYSTEMS, AND METHODS USING SAME Genentech, Inc. (US) 2023-04-19 EP claimed
US-20230038598-A1 MICROFLUIDIC PRODUCTION OF BIOFUNCTIONALIZED GIANT UNILAMELLAR VESICLES FOR TARGETED CARGO DELIVERY MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2023-02-09 US claimed
US-11446238-B2 Injectable dendrimer hydrogel nanoparticles WAYNE STATE UNIVERSITY (US) 2022-09-20 US claimed
EP-4054533-A1 BOTTOM-UP ASSEMBLY OF SYNTHETIC EXTRACELLULAR VESICLES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2022-09-14 EP claimed
EP-4054532-A1 MICROFLUIDIC PRODUCTION OF BIOFUNCTIONALIZED GIANT UNILAMELLAR VESICLES FOR TARGETED CARGO DELIVERY Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2022-09-14 EP claimed
WO-2021252803-A1 NANOLIPOPROTEIN-POLYPEPTIDE CONJUGATES AND COMPOSITIONS, SYSTEMS, AND METHODS USING SAME GENENTECH, INC. (US) 2021-12-16 WO claimed
WO-2021152115-A1 BOTTOM-UP ASSEMBLY OF SYNTHETIC EXTRACELLULAR VESICLES MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-08-05 WO claimed
EP-1813614-B1 Cytotoxic agents comprising new tomaymycin derivatives SANOFI SA (FR) 2011-10-05 EP claimed
US-20100092567-A1 IMMUNOSTIMULATORY NANOPARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2010-04-15 US claimed
US-20090311276-A1 NANOLIPOPROTEIN PARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS LAWRENCE LIVERMORE NATIONAL SECURITY, LLC 2009-12-17 US claimed
WO-2009143280-A2 NANOLIPOPROTEIN PARTICLES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2009-11-26 WO claimed
EP-0550663-B1 MODIFIED ANTIBODIES WITH CONTROLLED CLEARANCE TIME TECHNICLONE INC (US) 1998-01-21 EP claimed
EP-0783894-A1 Antibodies modified at two separate sites TECHNICLONE, INC. (US) 1997-07-16 EP claimed
EP-0339264-B1 Compounds for the introduction of a mercapto group to tyrosin BOEHRINGER MANNHEIM GMBH (DE) 1994-08-03 EP claimed
EP-0252951-A4 TECHNETIUM-ANTIBODY CONJUGATE. UNIV MELBOURNE (AU) 1988-09-07 EP claimed
EP-0252951-A1 TECHNETIUM-ANTIBODY CONJUGATE THE UNIVERSITY OF MELBOURNE (AU) 1988-01-20 EP claimed
WO-1987004164-A1 TECHNETIUM-ANTIBODY CONJUGATE THE UNIVERSITY OF MELBOURNE (AU) 1987-07-16 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230038598-A1 MICROFLUIDIC PRODUCTION OF BIOFUNCTIONALIZED GIANT UNILAMELLAR VESICLES FOR TARGETED CARGO DELIVERY PCNA, BOD1L1, SARS1 CYP1A2 4775/4885CYP3A4 4442/4885ALDH1A1 3690/4885
US-11446238-B2 Injectable dendrimer hydrogel nanoparticles PAM, UACA, FLT1 CYP1A2 3241/4885CYP3A4 3080/4885ALDH1A1 1885/4885
US-12569439-B2 Bottom-up assembly of synthetic extracellular vesicles EXOSC10, PLTP, EXOSC9 CYP1A2 4873/4885CYP3A4 4871/4885ALDH1A1 4712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.