Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 2/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28990301 | 0.80 | PTPN1 (0.64) | PGRPTPN1PTPN2ALDH1A1KDM4E | |
| SCHEMBL28988631 | 0.80 | PGR (0.46) | PGRPTPN1PTPN2TDP2ERN1 | |
| SCHEMBL30367335 | 0.80 | PGR (0.46) | PGRPTPN1PTPN2TDP2ERN1 | |
| SCHEMBL28990326 | 0.74 | PGR (0.48) | PGRPTPN1PTPN2ERN1ALDH1A1 | |
| SCHEMBL28990316 | 0.74 | PTPN1 (0.65) | PTPN1ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL28990318 | 0.71 | PTPN1 (0.61) | PTPN1ALDH1A1PIM1KDM4ESMN1; SMN2 | |
| SCHEMBL28990323 | 0.71 | PTPN1 (0.61) | PTPN1ALDH1A1HSD17B10 | |
| SCHEMBL29116198 | 0.71 | ALDH1A1 (0.55) | PTPN1ALDH1A1TSHRUSP2RAB9A | |
| SCHEMBL28269364 | 0.70 | ERN1 (0.54) | PGRTDP2ERN1ALDH1A1USP2 | |
| SCHEMBL25567716 | 0.70 | MAOB (0.56) | PTPN1ALDH1A1KDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115991695-B | Method for preparing 3-fluorochromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2024-06-21 | — | — | CN | disclosed |
| CN-115991695-A | Method for preparing 3-fluorochromanone by metal-free catalytic hydrogenation | 中国科学院化学研究所 | 2023-04-21 | — | — | CN | disclosed |