Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.82 |
| ▸ | ARG2 | P78540 | 4/20 | 0.54 |
| ▸ | ARG1 | P05089 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Ornithine SCHEMBL11698688 | 1.00 | GSR (0.82) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine Aketoglutarate SCHEMBL6265604 | 1.00 | GSR (0.82) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine SCHEMBL6265605 | 1.00 | GSR (0.82) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine Aketoglutarate SCHEMBL1326163 | 0.97 | GSR (0.86) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine Aketoglutarate SCHEMBL42530 | 0.97 | GSR (0.86) | GSRARG2ARG1CYP1A2GRM8 | |
| D-Ornithine SCHEMBL43724 | 0.97 | — | — | |
| Ornithine SCHEMBL624782 | 0.97 | GSR (0.86) | GSRARG2ARG1CYP1A2GRM8 | |
| D-Ornithine SCHEMBL1537220 | 0.97 | GSR (0.86) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine SCHEMBL20362354 | 0.97 | — | — | |
| Ornithine Aketoglutarate SCHEMBL8578 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116806157-A | Linker-payload and conjugates thereof | 芬兰吉利科斯有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-118359610-A | MENIN-MLL interaction inhibitors | 生命医药有限责任公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-110536703-B | Combination therapy using anti-AXL antibody-drug conjugates | ADC治疗有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-110381983-B | Chimeric proteins based on TIGIT and LIGHT | 沙塔克实验室有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-113840798-B | Functionalized enzyme driven nanomotor | 加泰罗尼亚生物工程基础研究所 | 2024-07-05 | — | — | CN | disclosed |
| CN-118234507-A | Endostatin peptides for treating tumors, fibrosis and acute lung injury | MUSC研究发展基金会 | 2024-06-21 | — | — | CN | disclosed |
| CN-118184797-A | VSIG 8-based chimeric proteins | 沙塔克实验室有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-109952309-B | Constitutive active cytokine receptors for cell therapy | 贝勒医学院 | 2024-06-07 | — | — | CN | disclosed |
| CN-110199018-B | Chimeric poxvirus compositions and uses thereof | 希望之城 | 2024-06-07 | — | — | CN | disclosed |
| CN-111787916-B | Dihydroceramide desaturase inhibitors for treating diseases | 森陶鲁斯治疗公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116648451-A | Antagonist compounds | 阿道尔克斯治疗有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-112424225-B | anti-PD-L1 antibodies and uses thereof | 桂林三金药业股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-116457335-A | Process for preparing 3-fluoro-5- (((1S, 2 aR) -1,3, 4-pentafluoro-2 a-hydroxy-2, 2a,3, 4-tetrahydro-1H-cyclopenta [ cd ] inden-7-yl) oxy) benzonitrile and polymorphs thereof | 尼坎治疗公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-116406259-A | Dosage form compositions comprising inhibitors of BTK and mutants thereof | 广州麓鹏制药有限公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-109890982-B | Method for diagnosing and treating cancer by expression status and mutation status of NRF2 and target genes downstream thereof | 基因泰克公司 | 2023-07-07 | — | — | CN | disclosed |
| CN-116322780-A | Compounds and uses thereof | 福宏治疗公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-110267686-B | Pyrrolobenzodiazepine-antibody conjugates | ADC治疗有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-116096710-A | 4-oxo-3, 4-dihydroquinazolinone compounds for the treatment of BRAF related diseases and disorders | 阿雷生物药品公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115996929-A | Antagonists of adenosine A2a receptors | 阿道尔克斯治疗有限公司 | 2023-04-21 | — | — | CN | disclosed |