Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.82 |
| ▸ | ARG2 | P78540 | 4/20 | 0.54 |
| ▸ | ARG1 | P05089 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Ornithine SCHEMBL11698688 | 1.00 | GSR (0.82) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine SCHEMBL6265605 | 1.00 | GSR (0.82) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine Aketoglutarate SCHEMBL28990880 | 1.00 | GSR (0.82) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine Aketoglutarate SCHEMBL1326163 | 0.97 | GSR (0.86) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine Aketoglutarate SCHEMBL42530 | 0.97 | GSR (0.86) | GSRARG2ARG1CYP1A2GRM8 | |
| D-Ornithine SCHEMBL43724 | 0.97 | — | — | |
| Ornithine SCHEMBL624782 | 0.97 | GSR (0.86) | GSRARG2ARG1CYP1A2GRM8 | |
| D-Ornithine SCHEMBL1537220 | 0.97 | GSR (0.86) | GSRARG2ARG1CYP1A2GRM8 | |
| Ornithine SCHEMBL20362354 | 0.97 | — | — | |
| Ornithine Aketoglutarate SCHEMBL8578 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110381960-A | The bicarbonate of reinforcing agent as antimicrobial | 麦克马斯特大学 | 2019-10-25 | — | — | CN | claimed |
| CN-110191876-A | FORMULATIONS FOR ADMINISTRATION OF EFLORNITHINE | 奥巴斯治疗股份有限公司 | 2019-08-30 | — | — | CN | claimed |
| CN-109152758-A | The composition and method of the cancer including glioma are treated using Eflornithine and the like and derivative | 奥巴斯医疗股份有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-117530943-A | Formulations for administration of efluromithine | 奥巴斯治疗股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-115698321-A | Methods for plasma free RNA analysis | 格里尔公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-114096240-A | Method for treating familial adenomatous polyposis | 癌症预防制药股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-112955438-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | 卡里科生命科学有限责任公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-112812183-A | anti-IL-36R antibodies | 勃林格殷格翰国际有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112204009-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-107007833-B | anti-IL-36R antibodies | 勃林格殷格翰国际有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-110191876-A | FORMULATIONS FOR ADMINISTRATION OF EFLORNITHINE | 奥巴斯治疗股份有限公司 | 2019-08-30 | — | — | CN | disclosed |
| US-5519115-A | BACTERICIDES OR FUNGICIDES | ENICHEM S.P.A. (IT) | 1996-05-21 | — | — | US | disclosed |
| US-5424395-A | Magainins | ENICHEM S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| CN-1027891-C | Process for the preparation of 5-substituted ornithine derivatives | MERRELL DOW PHARMA (US) | 1995-03-15 | — | — | CN | disclosed |
| CN-1021817-C | Process for preparing polyamine derivatives | MERRELL DOW PHARMA (US) | 1993-08-18 | — | — | CN | disclosed |
| EP-0497366-A2 | Antimicrobial peptides and their use against plant pathogens | ENICHEM S.p.A. (IT) | 1992-08-05 | — | — | EP | disclosed |
| EP-0472987-A1 | Antimicrobial peptides active against plant pathogens, their use and screening methods pertaining thereto | ENICHEM S.p.A. (IT) | 1992-03-04 | — | — | EP | disclosed |
| CN-1039422-A | New S-adenosyl methionine decarboxylase inhibitor | MERRELL DOW PHARMA (US) | 1990-02-07 | — | — | CN | disclosed |
| CN-1037142-A | The 5-substituted ornithine derivatives | MERRELL DOW PHARMA (US) | 1989-11-15 | — | — | CN | disclosed |
| CN-88100500-A | NOVEL POLYAMINE DERIVATIVES | — | 1988-09-07 | — | — | CN | disclosed |