Biphenyl

Biphenyl

SCHEMBL28994599

O=S(O)O.[KH].c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
MMP3 P08254 1/20 0.48
BCL2L1 Q07817 1/20 0.48
MAPT P10636 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LMNA P02545 2/20 0.42
HTT P42858 2/20 0.42
ABCC4 O15439 1/20 0.42
GAA P10253 1/20 0.42
TSHR P16473 1/20 0.42
PTGS1 P23219 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
MGLL Q99685 1/20 0.42
MAPK1 P28482 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL278264 0.97 ALDH1A1 (0.60) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL10391914 0.84 ALDH1A1 (0.45) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL15610250 0.83 ALDH1A1 (0.69) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL28994601 0.82 ALDH1A1 (0.50) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
SCHEMBL11325723 0.82 MMP3 (0.44) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL27650730 0.79 ALDH1A1 (0.75) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL11037814 0.79 ALDH1A1 (0.90) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL3888058 0.79 ALDH1A1 (0.90) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
Biphenyl SCHEMBL28098924 0.79 ALDH1A1 (0.90) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2
SCHEMBL10011964 0.78 MMP3 (0.46) ALDH1A1MMP3BCL2L1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116963738-A Luminol for the prevention and treatment of sequelae of SARS-CoV-2 infection 麦翠奥制药公司 2023-10-27 CN disclosed
CN-116075306-A Compounds for the treatment of coronavirus infections 麦翠奥制药公司 2023-05-05 CN disclosed