Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30365121 | 0.80 | CYP3A4 (0.33) | FFAR4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL3186957 | 0.80 | CYP3A4 (0.33) | FFAR4CYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL25210351 | 0.77 | CYP3A4 (0.35) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL16231411 | 0.69 | SIRT1 (0.40) | LMNACYP3A4CHRM1ALOX15MAOA | |
| SCHEMBL11804375 | 0.67 | LMNA (0.44) | LMNATDP1FFAR4ALDH1A1 | |
| SCHEMBL10576669 | 0.67 | CA1 (0.34) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL27804376 | 0.67 | CA2 (0.38) | LMNATDP1ALDH1A1GAA | |
| SCHEMBL31465325 | 0.67 | CYP3A4 (0.43) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL31497683 | 0.67 | CYP3A4 (0.43) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL1019625 | 0.67 | CYP3A4 (0.43) | CYP3A4CHRM1ALOX15MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185858-B1 | COMPOSITIONS, SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS USING DYES | LIFE TECHNOLOGIES CORP (US) | 2025-05-21 | — | — | EP | disclosed |
| US-20240060117-A1 | ENERGY TRANSFER DYE CONJUGATES FOR USE IN BIOLOGICAL ASSAYS | Life Technologies Corporation | 2024-02-22 | — | — | US | disclosed |
| US-20230304932-A1 | COMPOSITIONS, SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS INVOLVING ENERGY TRANSFER DYE CONJUGATES AND ANALYTES COMPRISING THE SAME | Life Technologies Corporation | 2023-09-28 | — | — | US | disclosed |
| CN-116323965-A | Compositions, systems and methods for bioassays using dyes | 生命技术公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-4185858-A2 | COMPOSITIONS, SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS USING DYES | Life Technologies Corporation (US) | 2023-05-31 | — | — | EP | disclosed |
| EP-4185596-A1 | ENERGY TRANSFER DYE CONJUGATES FOR USE IN BIOLOGICAL ASSAYS | Life Technologies Corporation (US) | 2023-05-31 | — | — | EP | disclosed |
| CN-116075597-A | Energy transfer dye conjugates for use in bioassays | 生命技术公司 | 2023-05-05 | — | — | CN | disclosed |