SCHEMBL28995152

SCHEMBL28995152

C=C(C)C(=O)N(Cc1ccccc1)c1ccc(Cl)cc1Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 1/20 0.40
PPARA Q07869 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
GAA P10253 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
PDK1 Q15118 1/20 0.39
TMEM97 Q5BJF2 2/20 0.38
SIGMAR1 Q99720 2/20 0.38
HPGD P15428 1/20 0.37
HTT P42858 3/20 0.37
ALDH1A1 P00352 3/20 0.37
LMNA P02545 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
PAX8 Q06710 2/20 0.37
GLA P06280 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28995158 0.87 TSPO (0.42) TSPOSMN1; SMN2KMT2ATMEM97SIGMAR1
SCHEMBL28995155 0.86 TSPO (0.47) TSPOSMN1; SMN2MEN1KMT2AHPGD
SCHEMBL28995170 0.85 TSPO (0.40) TSPOSMN1; SMN2MEN1KMT2AHPGD
SCHEMBL28850407 0.84 HPGD (0.46) TSPOSMN1; SMN2MEN1KMT2ASIGMAR1
SCHEMBL28995153 0.84 TSHR (0.45) TSPOSMN1; SMN2MEN1KMT2AHTT
SCHEMBL28995157 0.79 TSPO (0.47) TSPOMEN1KMT2AHPGDHTT
SCHEMBL28995164 0.74 TRPM8 (0.50) TSPOSMN1; SMN2MEN1KMT2AHPGD
SCHEMBL28078011 0.73 NPC1 (0.56) TSPOSMN1; SMN2GAAMEN1KMT2A
SCHEMBL28948520 0.73 TRPM8 (0.44) TSPOSMN1; SMN2MEN1KMT2AHTT
SCHEMBL31223924 0.73 HPGD (0.39) TSPOSMN1; SMN2GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116043243-B Method for electrochemically synthesizing 3, 4-dihydro-quinolinone compounds 桂林电子科技大学 2025-02-18 CN disclosed
CN-116043243-A Method for electrochemically synthesizing 3, 4-dihydro-quinolinone compounds 桂林电子科技大学 2023-05-02 CN disclosed