Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 8/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 5/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | BID | P55957 | 2/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29369539 | 1.00 | RORC (0.35) | RORCBTKFFAR1BCL2A1SCN9A | |
| SCHEMBL28996908 | 0.80 | FFAR1 (0.49) | FFAR1BCL2A1 | |
| SCHEMBL29369830 | 0.80 | FFAR1 (0.49) | FFAR1BCL2A1 | |
| SCHEMBL28997016 | 0.78 | FFAR1 (0.44) | FFAR1BCL2A1 | |
| SCHEMBL29369580 | 0.78 | FFAR1 (0.44) | FFAR1BCL2A1 | |
| SCHEMBL26124919 | 0.76 | TGM2 (0.40) | TGM2 | |
| SCHEMBL28996992 | 0.76 | TGM2 (0.40) | TGM2 | |
| SCHEMBL29366854 | 0.71 | TRPV1 (0.41) | TGM2 | |
| SCHEMBL28996931 | 0.71 | TRPV1 (0.41) | TGM2 | |
| SCHEMBL28997072 | 0.70 | TGM2 (0.38) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | claimed |
| CN-116057042-A | Acrylamide-substituted indane compounds and their therapeutic uses | 赛诺菲 | 2023-05-02 | — | — | CN | disclosed |