Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16127308 | 0.83 | TRPV4 (0.52) | TRPV4DHODHKDM4EALDH1A1MAPT | |
| SCHEMBL9490015 | 0.83 | TRPV4 (0.56) | TRPV4DHODH | |
| SCHEMBL7072456 | 0.82 | TRPV4 (0.46) | TRPV4DHODHKDM4EALDH1A1MAPT | |
| SCHEMBL13082286 | 0.82 | TRPV4 (0.41) | TRPV4DHODHKDM4EALDH1A1MAPT | |
| SCHEMBL27521579 | 0.81 | TRPV4 (0.42) | TRPV4DHODHKDM4EALDH1A1HPGD | |
| SCHEMBL22829054 | 0.81 | TRPV4 (0.42) | TRPV4DHODHKDM4ELMNAATM | |
| SCHEMBL29728453 | 0.78 | TRPV4 (0.52) | TRPV4 | |
| SCHEMBL809217 | 0.78 | TRPV4 (0.52) | TRPV4 | |
| SCHEMBL8116820 | 0.77 | HDAC1 (0.32) | — | |
| SCHEMBL3191466 | 0.77 | TRPV4 (0.46) | TRPV4DHODHKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210159421-A1 | COMPOSITION FOR FORMING CHARGE-TRANSPORTING THIN FILM | NISSAN CHEMICAL CORPORATION (JP) | 2021-05-27 | — | — | US | disclosed |
| EP-3053910-B1 | ANILINE DERIVATIVES AND USES THEREOF | NISSAN CHEMICAL CORP (JP) | 2021-04-28 | — | — | EP | disclosed |
| EP-3109914-B1 | CHARGE-TRANSPORTING VARNISH | NISSAN CHEMICAL CORP (JP) | 2021-04-28 | — | — | EP | disclosed |
| US-10700283-B2 | Aniline derivatives and uses thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2020-06-30 | — | — | US | disclosed |
| US-20200032140-A1 | CHARGE-TRANSPORTING VARNISH | NISSAN CHEMICAL CORPORATION (JP) | 2020-01-30 | — | — | US | disclosed |
| EP-3425689-B1 | CHARGE-TRANSPORTING VARNISH | NISSAN CHEMICAL CORP (JP) | 2019-10-23 | — | — | EP | disclosed |
| US-10301484-B2 | Varnish for formation of charge-transporting thin film | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2019-05-28 | — | — | US | disclosed |
| EP-3425689-A1 | CHARGE-TRANSPORTING VARNISH | Nissan Chemical Corporation (JP) | 2019-01-09 | — | — | EP | disclosed |
| EP-3270433-A1 | COMPOSITION FOR FORMING CHARGE-TRANSPORTING THIN FILM FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, CHARGE-TRANSPORTING THIN FILM FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT | Nissan Chemical Industries, Ltd. (JP) | 2018-01-17 | — | — | EP | disclosed |
| US-20180002539-A1 | VARNISH FOR FORMATION OF CHARGE-TRANSPORTING THIN FILM | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-01-04 | — | — | US | disclosed |
| US-20170213986-A1 | CHARGE TRANSPORT MATERIAL | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-07-27 | — | — | US | disclosed |
| US-20170213986-A1 | CHARGE TRANSPORT MATERIAL | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-07-27 | — | — | US | disclosed |
| EP-3174115-A1 | CHARGE TRANSPORT MATERIAL | Nissan Chemical Industries, Ltd. (JP) | 2017-05-31 | — | — | EP | disclosed |
| US-20160301011-A1 | ANILINE DERIVATIVES AND USES THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-10-13 | — | — | US | disclosed |
| US-20160301011-A1 | ANILINE DERIVATIVES AND USES THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-10-13 | — | — | US | disclosed |
| EP-3053910-A1 | ANILINE DERIVATIVES AND USES THEREOF | Nissan Chemical Industries, Ltd. (JP) | 2016-08-10 | — | — | EP | disclosed |
| WO-2016117521-A1 | VARNISH FOR FORMATION OF CHARGE-TRANSPORTING THIN FILM | 日産化学工業株式会社 | 2016-07-28 | — | — | WO | disclosed |
| WO-2016013533-A1 | CHARGE TRANSPORT MATERIAL | 日産化学工業株式会社 | 2016-01-28 | — | — | WO | disclosed |
| EP-2427801-A1 | FUNCTIONALIZED PERFLUOROPOLYETHER MATERIAL AS A HYDROPHOBIC COATING | Hewlett-Packard Development Company, L.P. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128969-A1 | FUNCTIONALIZED PERFLUOROPOLYETHER MATERIAL AS A HYDROPHOBIC COATING | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160301011-A1 | ANILINE DERIVATIVES AND USES THEREOF | SLC18A1, SLC18A2, SLC43A1 | TRPV4 279/4885DHODH 2077/4885KDM4E 3212/4885 |
| US-10700283-B2 | Aniline derivatives and uses thereof | SLC18A1, SLC18A2, SLC43A1 | TRPV4 279/4885DHODH 2077/4885KDM4E 3212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.