Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108267 | 0.92 | LMNA (0.62) | ALDH1A1LMNAKMT2ASMN1; SMN2HDAC3 | |
| SCHEMBL7545834 | 0.89 | LMNA (0.69) | ALDH1A1FAAHLMNASMN1; SMN2 | |
| SCHEMBL28999858 | 0.89 | LMNA (0.69) | ALDH1A1FAAHLMNASMN1; SMN2 | |
| SCHEMBL179083 | 0.88 | LMNA (0.64) | ALDH1A1POLBHTTFAAHTDP1 | |
| SCHEMBL28999835 | 0.88 | FAAH (0.60) | ALDH1A1FAAHLMNAKMT2AHDAC3 | |
| SCHEMBL5191013 | 0.86 | ALDH1A1 (0.60) | ALDH1A1POLBHTTLMNAKMT2A | |
| SCHEMBL28999833 | 0.85 | FAAH (0.64) | ALDH1A1FAAHLMNASMN1; SMN2 | |
| SCHEMBL28999856 | 0.84 | KMT2A (0.57) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9425938 | 0.84 | KMT2A (0.60) | ALDH1A1HTTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL31011325 | 0.84 | TDP1 (0.77) | ALDH1A1POLBHTTFAAHTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400573-B | Benzo [ d ] [1,3] dioxole compound, preparation method and application thereof | 中国人民解放军第二军医大学 | 2023-04-11 | — | — | CN | claimed |
| CN-109400573-B | Benzo [ d ] [1,3] dioxole compound, preparation method and application thereof | 中国人民解放军第二军医大学 | 2023-04-11 | — | — | CN | disclosed |