Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 5/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.51 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.51 |
| ▸ | CYP3A43 | Q9HB55 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.49 |
| ▸ | CTRL | P40313 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.48 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28999982 | 0.94 | REN (0.53) | RENMMP1MMP3MMP9CYP3A4 | |
| SCHEMBL13893311 | 0.90 | BIRC2 (0.54) | RENCYP3A4CYP3A5CYP3A7CYP3A43 | |
| SCHEMBL84540 | 0.90 | BIRC2 (0.54) | RENCYP3A4CYP3A5CYP3A7CYP3A43 | |
| SCHEMBL19474595 | 0.90 | BIRC2 (0.54) | RENCYP3A4CYP3A5CYP3A7CYP3A43 | |
| SCHEMBL17629488 | 0.87 | ACE (0.55) | MMP3MMP9CYP3A4CYP3A5CYP3A7 | |
| SCHEMBL17629489 | 0.87 | ACE (0.55) | MMP3MMP9CYP3A4CYP3A5CYP3A7 | |
| SCHEMBL2633256 | 0.87 | ACE (0.55) | MMP3MMP9CYP3A4CYP3A5CYP3A7 | |
| SCHEMBL16254086 | 0.86 | TMPRSS11D (0.48) | MMP1MMP3CYP3A4CYP3A5CYP3A7 | |
| SCHEMBL28599750 | 0.84 | CTSK (0.53) | RENMMP1MMP3MMP9POLB | |
| SCHEMBL15624933 | 0.84 | MAPT (0.57) | MMP1MMP3MMP9POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024637-B | Method for preparing carfilzomib by taking water-soluble alkynylamide as condensing agent | 江西师范大学 | 2023-05-16 | — | — | CN | disclosed |