Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29003177 | 1.00 | GPR119 (0.42) | GPR119SLC6A7NR1H2NR1H3MMP2 | |
| SCHEMBL29412824 | 0.85 | GPR119 (0.60) | GPR119 | |
| SCHEMBL29003150 | 0.85 | GPR119 (0.60) | GPR119 | |
| SCHEMBL24348654 | 0.85 | GPR119 (0.60) | GPR119 | |
| SCHEMBL29003128 | 0.81 | SLC6A7 (0.40) | GPR119SLC6A7MMP2ALDH1A1 | |
| SCHEMBL29003133 | 0.81 | SLC6A7 (0.40) | GPR119SLC6A7MMP2ALDH1A1 | |
| SCHEMBL16822 | 0.74 | SLC6A7 (0.49) | GPR119SLC6A7KCNH2 | |
| SCHEMBL18152253 | 0.74 | SLC6A7 (0.49) | GPR119SLC6A7KCNH2 | |
| SCHEMBL5476032 | 0.74 | SLC6A7 (0.49) | GPR119SLC6A7KCNH2 | |
| SCHEMBL24349653 | 0.72 | GPR119 (0.49) | GPR119NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157122-A | Imidazo [1,2-a ] pyridine compounds and their use in therapy | 帝国理工学院创新有限公司 | 2023-05-23 | — | — | CN | disclosed |