SCHEMBL29004685

SCHEMBL29004685

CCCC(CO)CCC(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
CA12 O43570 4/20 0.40
CA14 Q9ULX7 4/20 0.40
CA2 P00918 2/20 0.40
CA1 P00915 1/20 0.40
SLC1A1 P43005 1/20 0.40
LMNA P02545 3/20 0.39
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 2/20 0.35
MAPK1 P28482 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
KDM5A P29375 2/20 0.35
ALDH1A1 P00352 2/20 0.34
HTT P42858 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15187351 1.00 TSHR (0.46) TSHRCA12CA14CA2CA1
SCHEMBL15187352 1.00 TSHR (0.46) TSHRCA12CA14CA2CA1
SCHEMBL17526723 0.89 TSHR (0.50) TSHRCA12CA14CA2CA1
SCHEMBL17526659 0.89 TSHR (0.50) TSHRCA12CA14CA2CA1
SCHEMBL15187093 0.89 ALDH1A1 (0.50) TSHRCA12CA14CA2CA1
SCHEMBL5000221 0.87 TSHR (0.55) TSHRCA12CA14SLC1A1LMNA
SCHEMBL17526393 0.87 LMNA (0.48) TSHRLMNAKMT2AMEN1L3MBTL1
SCHEMBL17526409 0.87 LMNA (0.48) TSHRLMNAKMT2AMEN1L3MBTL1
SCHEMBL17526968 0.86 TSHR (0.44) TSHRCA12CA14CA2CA1
SCHEMBL17526834 0.86 TSHR (0.44) TSHRCA12CA14CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960074-A Fluorine-containing ferroelectric liquid crystal molecules containing heteroatom hexatomic alicyclic ring and synthesis method thereof 华南理工大学 2023-04-14 CN disclosed