SCHEMBL5000221

SCHEMBL5000221

COC(=O)CCC(CO)CO

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
SLC1A1 P43005 1/20 0.44
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 3/20 0.40
CA12 O43570 2/20 0.40
CA14 Q9ULX7 2/20 0.40
KDM4E B2RXH2 1/20 0.40
HSD17B10 Q99714 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.39
HTT P42858 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15187351 0.87 TSHR (0.46) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL29004685 0.87 TSHR (0.46) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL15187352 0.87 TSHR (0.46) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL15187093 0.84 ALDH1A1 (0.50) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL15183786 0.82 TSHR (0.41) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL15183784 0.82 TSHR (0.41) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL9606840 0.81 TSHR (0.55) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL10044830 0.81 TSHR (0.55) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL17526858 0.80 TSHR (0.48) TSHRSLC1A1KMT2AMEN1LMNA
SCHEMBL17526925 0.80 TSHR (0.48) TSHRSLC1A1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7241914-B2 Method for producing polyesterpolyols of polyvalent alcohols BASF AKTIENGESELLSCHAFT (DE) 2007-07-10 US claimed
US-20050148802-A1 Method for producing polyetherols BASF AKTIENGESELLSCHAFT 2005-07-07 US claimed
US-20050010065-A1 Method for producing (meth) acrylic acid esters of polyhydric alcohols BASF AKTIENGESELLSCHAFT (DE) 2005-01-13 US claimed
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2026-05-28 US disclosed
US-12539332-B2 Anti-viral and hepatic-targeted drugs A-BIOPHARMA (FR) 2026-02-03 US disclosed
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS AI-BIOPHARMA (FR) 2024-05-02 US disclosed
EP-4045504-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS Ai-biopharma (FR) 2022-08-24 EP disclosed
US-20170327626-A1 METHOD FOR PRODUCING RADIATION-CURABLE URETHANE (METH)ACRYLATES UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA 2017-11-16 US disclosed
EP-1741717-B1 Metal nanostructures and pharmaceutical compositions IMEC INTER UNI MICRO ELECTR (BE) 2009-01-28 EP disclosed
US-7420013-B2 Mixtures of compounds comprising at least two double bonds and use thereof BASF AKTIENGESELLSCHAFT (DE) 2008-09-02 US disclosed
US-7250481-B2 Reacting polyalcohol with at least one ethylenically unsaturated carboxylic acid in the presence of at least one esterification catalyst and of at least one polymerization inhibitor, polymerizing the reaction mixture, in the presence of at least one radical initiator, postcrosslinking, drying BASF AKTIENGESELLSCHAFT (DE) 2007-07-31 US disclosed
US-7241914-B2 Method for producing polyesterpolyols of polyvalent alcohols BASF AKTIENGESELLSCHAFT (DE) 2007-07-10 US disclosed
US-20070129564-A1 Method for the production of (meth)acrylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-06-07 US disclosed
US-20060235141-A1 Mixtures of compounds comprising at least two double bonds and use thereof BASF AKTIENGESELLSCHAFT (DE) 2006-10-19 US disclosed
US-20060052571-A1 Method for the production of radiation-curable urethane (meth) acrylates BASF AKITIENGESELLSCHAFT (DE) 2006-03-09 US disclosed
US-20050203268-A1 Method for producing polyesterpolyols of polyvalent alcohols BASF AKTIENGESELLSCHAFT (DE) 2005-09-15 US disclosed
US-20050176910-A1 Method for the production of esters of polyalcohols BASF AKTIENGESELLSCHAFT (DE) 2005-08-11 US disclosed
US-20050148802-A1 Method for producing polyetherols BASF AKTIENGESELLSCHAFT 2005-07-07 US disclosed
US-20050010065-A1 Method for producing (meth) acrylic acid esters of polyhydric alcohols BASF AKTIENGESELLSCHAFT (DE) 2005-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539332-B2 Anti-viral and hepatic-targeted drugs HAVCR2, NR1H4, NR1H3 TSHR 811/4885SLC1A1 1075/4885KMT2A 4322/4885
US-20260144879-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS HAVCR2, NR1H4, NR1H3 TSHR 1033/4885SLC1A1 1211/4885KMT2A 4167/4885
US-20070129564-A1 Method for the production of (meth)acrylic acid esters MMAB, ACR, MCCC2 TSHR 2304/4885SLC1A1 1996/4885KMT2A 1058/4885
US-20050010065-A1 Method for producing (meth) acrylic acid esters of polyhydric alcohols ADH1A, ADH1C, ADH5 TSHR 2220/4885SLC1A1 2385/4885KMT2A 432/4885
US-20050148802-A1 Method for producing polyetherols ADH1A, ADH1C, ADH5 TSHR 3289/4885SLC1A1 4306/4885KMT2A 509/4885
US-20240139325-A1 ANTI-VIRAL AND HEPATIC-TARGETED DRUGS SLC10A1, HAVCR2, HDGF TSHR 4110/4885SLC1A1 1223/4885KMT2A 4427/4885
US-20050203268-A1 Method for producing polyesterpolyols of polyvalent alcohols ADH1C, ADH1A, ADH5 TSHR 4473/4885SLC1A1 3230/4885KMT2A 634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.