Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30342159 | 0.85 | MAPT (0.48) | S1PR3PPARGPPARAALDH1A1MAPT | |
| SCHEMBL29005338 | 0.75 | S1PR3 (0.51) | S1PR3PPARGPPARAALDH1A1MAPT | |
| SCHEMBL2009327 | 0.75 | SLC6A9 (0.64) | S1PR3CNR1CTSSCTSKSLC6A9 | |
| SCHEMBL29005216 | 0.74 | PRCP (0.49) | CNR1SLC6A9SLC6A5 | |
| SCHEMBL4289099 | 0.72 | S1PR3 (0.53) | S1PR3PPARGPPARAALDH1A1MAPT | |
| SCHEMBL999536 | 0.72 | S1PR3 (0.53) | S1PR3PPARGPPARAALDH1A1MAPT | |
| SCHEMBL4277192 | 0.72 | S1PR3 (0.53) | S1PR3PPARGPPARAALDH1A1MAPT | |
| SCHEMBL3946429 | 0.71 | GAA (0.44) | PPARGPPARAALDH1A1MAPTCTSL | |
| SCHEMBL391359 | 0.71 | TRPA1 (0.47) | S1PR3PPARGPPARAALDH1A1MAPT | |
| SCHEMBL27159043 | 0.71 | GAA (0.44) | PPARGPPARAALDH1A1MAPTCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |