SCHEMBL29005203

SCHEMBL29005203

NCC(NCCO)C(=O)NC(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.43
AKT1 P31749 1/20 0.42
PRCP P42785 3/20 0.40
GABBR2 O75899 3/20 0.40
GABBR1 Q9UBS5 3/20 0.40
LMNA P02545 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP3A4 P08684 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
NFKB1 P19838 1/20 0.40
DRD3 P35462 1/20 0.40
BLM P54132 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
MEN1 O00255 1/20 0.40
THRB P10828 1/20 0.40
TSHR P16473 1/20 0.40
KMT2A Q03164 1/20 0.40
SLC6A9 P48067 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29005197 0.83 CYP1A2 (0.41) CNR1AKT1PRCPCYP1A2CYP2D6
Benzyl Benzoate SCHEMBL30345166 0.83 KMT2A (0.44) CNR1PRCPLMNACYP2C9CYP3A4
SCHEMBL30342183 0.74 CTSK (0.48) LMNACYP3A4TSHRSLC6A9SLC6A5
SCHEMBL4001999 0.66 SLC6A9 (0.63) CNR1PRCPLMNACYP2C9CYP2D6
SCHEMBL31579895 0.65 HTR1A (0.47) AKT1LMNACYP3A4ADORA3DRD3
Hydrochloric Acid SCHEMBL30375714 0.65 PRCP (0.49) CNR1PRCPHDAC4HDAC7HDAC5
Hydrochloric Acid SCHEMBL10526098 0.65 MDM2 (0.48) AKT1LMNABLMMEN1KMT2A
Hydrochloric Acid SCHEMBL2010289 0.65 SLC6A9 (0.62) CNR1PRCPLMNACYP2C9CYP2D6
SCHEMBL1732731 0.65 CNR1 (0.59) CNR1CYP1A2MEN1KMT2ASLC6A9
SCHEMBL30345267 0.64 CYP1A2 (0.46) CNR1PRCPCYP1A2CYP2D6SLC6A9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116134018-A 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor 默沙东有限责任公司 2023-05-16 CN disclosed