Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | PRCP | P42785 | 4/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29005203 | 0.83 | CNR1 (0.43) | CYP1A2AKT1CNR1PRCPSLC6A9 | |
| SCHEMBL30345267 | 0.78 | CYP1A2 (0.46) | CYP1A2CNR1PRCPSLC6A9SLC6A5 | |
| Hydrochloric Acid SCHEMBL29005165 | 0.78 | CYP1A2 (0.46) | CYP1A2CNR1PRCPSLC6A9SLC6A5 | |
| Benzyl Benzoate SCHEMBL30345166 | 0.74 | KMT2A (0.44) | CYP1A2CNR1PRCPSLC6A9SLC6A5 | |
| SCHEMBL30342183 | 0.74 | CTSK (0.48) | SLC6A9SLC6A5SMN1; SMN2ALDH1A1 | |
| SCHEMBL22479163 | 0.68 | CTSS (0.48) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL22479162 | 0.65 | CYP1A2 (0.57) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL18010560 | 0.62 | LMNA (0.70) | CNR1SLC6A9SLC6A5ALDH1A1 | |
| SCHEMBL31579895 | 0.61 | HTR1A (0.47) | CYP1A2AKT1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL11314021 | 0.61 | MAPT (0.50) | CYP1A2SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134018-A | 2-oxoimidazolidine-4-carboxamide as NAV1.8 inhibitor | 默沙东有限责任公司 | 2023-05-16 | — | — | CN | disclosed |