Anisole

Anisole

SCHEMBL29005803

Brc1cccc(C=Cc2ccccc2)c1Br.COc1ccccc1

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.56
NFE2L2 Q16236 8/20 0.51
RELA Q04206 5/20 0.50
CYP1A1 P04798 2/20 0.49
CYP1A2 P05177 2/20 0.49
CYP1B1 Q16678 2/20 0.49
PPARG P37231 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MEN1 O00255 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TRPV1 Q8NER1 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CA4 P22748 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4951414 0.87 NFE2L2 (0.50) TRPA1NFE2L2MEN1KMT2A
SCHEMBL297693 0.87 NFE2L2 (0.50) TRPA1NFE2L2MEN1KMT2A
Anisole SCHEMBL29005748 0.76 NFE2L2 (0.84) TRPA1NFE2L2RELACYP1A1CYP1A2
SCHEMBL27955469 0.74 CYP1A1 (0.64) TRPA1NFE2L2RELACYP1A1CYP1A2
SCHEMBL631996 0.74 TRPA1 (0.76) TRPA1NFE2L2RELACYP1A1CYP1A2
SCHEMBL631997 0.74 TRPA1 (0.76) TRPA1NFE2L2RELACYP1A1CYP1A2
SCHEMBL699620 0.73 TRPA1 (1.00) TRPA1NFE2L2RELACYP1A1CYP1A2
SCHEMBL699621 0.73 TRPA1 (1.00) TRPA1NFE2L2RELACYP1A1CYP1A2
SCHEMBL8845585 0.73 TRPA1 (1.00) TRPA1NFE2L2RELACYP1A1CYP1A2
SCHEMBL6737772 0.73 NFE2L2 (0.56) TRPA1NFE2L2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979917-B Isocyanate composition, method for producing isocyanate composition, and method for producing isocyanate polymer 旭化成株式会社 2023-04-25 CN disclosed