SCHEMBL6737772

SCHEMBL6737772

Brc1ccccc1/C=C/c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 5/20 0.56
TRPA1 O75762 2/20 0.56
HSD11B1 P28845 1/20 0.52
CHRNA7 P36544 1/20 0.46
MAOB P27338 2/20 0.46
CYP19A1 P11511 1/20 0.44
MAOA P21397 1/20 0.44
NPC1 O15118 1/20 0.44
MTOR P42345 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
GRM4 Q14833 1/20 0.42
EGFR P00533 1/20 0.42
PTPN1 P18031 1/20 0.42
CHAT P28329 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30364986 1.00 NFE2L2 (0.56) NFE2L2TRPA1HSD11B1CHRNA7MAOB
SCHEMBL14703725 1.00 NFE2L2 (0.56) NFE2L2TRPA1HSD11B1CHRNA7MAOB
SCHEMBL6737776 1.00 NFE2L2 (0.56) NFE2L2TRPA1HSD11B1CHRNA7MAOB
SCHEMBL3328957 0.93 HSD11B1 (0.54) NFE2L2TRPA1HSD11B1CHRNA7NPC1
SCHEMBL3328961 0.93 HSD11B1 (0.54) NFE2L2TRPA1HSD11B1CHRNA7NPC1
SCHEMBL297691 0.87 HSD11B1 (0.62) NFE2L2HSD11B1CHRNA7NPC1MEN1
SCHEMBL1751871 0.87 HSD11B1 (0.62) NFE2L2HSD11B1CHRNA7NPC1MEN1
SCHEMBL8900317 0.87 HSD11B1 (0.62) NFE2L2HSD11B1CHRNA7NPC1MEN1
SCHEMBL31613215 0.87 HSD11B1 (0.62) NFE2L2HSD11B1CHRNA7NPC1MEN1
SCHEMBL28706684 0.87 HDAC2 (0.46) NFE2L2TRPA1HSD11B1CHRNA7MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12291593-B2 Compounds for use in catalyst compositions for the production of polyolefins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-05-06 US disclosed
EP-4031592-B1 COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-04-30 EP disclosed
CN-114423769-B Compounds in catalyst compositions for the production of polyolefins SABIC环球技术有限责任公司 2024-04-26 CN disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 US disclosed
US-20230234900-A1 METHODS OF ARENE ALKENYLATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION 2023-07-27 US disclosed
CN-114195610-B Synthesis method of E-type internal olefin compound 海南大学 2023-07-14 CN disclosed
WO-2023062575-A1 CYCLIC VINYL SULFONE COMPOUNDS AS WRN INHIBITORS IDEAYA BIOSCIENCES, INC. (US) 2023-04-20 WO disclosed
US-20220356275-A1 COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-11-10 US disclosed
EP-4031592-A1 COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS SABIC Global Technologies B.V. (NL) 2022-07-27 EP disclosed
CN-114423769-A Compounds for use in catalyst compositions for the production of polyolefins SABIC环球技术有限责任公司 2022-04-29 CN disclosed
EP-0629609-A1 Process for the preparation of Alkoxyiminoacetamide derivatives and an intermediate therefor SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1994-12-21 EP disclosed
US-5371222-A Intermediates SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 US disclosed
US-5371223-A Controlling phytopathogens SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1994-12-06 US disclosed
US-5315025-A Acrylate ethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-05-24 US disclosed
US-5286894-A Phenyl acrylic acid derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-02-15 US disclosed
US-5185342-A ALKOXYIMINOACETAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) 1993-02-09 US disclosed
EP-0178826-B1 FUNGICIDES ZENECA LIMITED (GB) 1991-12-18 EP disclosed
EP-0431328-A2 Fungicides ZENECA LIMITED (GB) 1991-06-12 EP disclosed
EP-0398692-A2 Alkoxyiminoacetamide derivatives and their use as fungicides SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-11-22 EP disclosed
EP-0178826-A2 Fungicides ZENECA LIMITED (GB) 1986-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220356275-A1 COMPOUNDS FOR USE IN CATALYST COMPOSITIONS FOR THE PRODUCTION OF POLYOLEFINS RPLP0, RPS20, RPS10 NFE2L2 2039/4885TRPA1 1692/4885HSD11B1 1831/4885
US-20230234900-A1 METHODS OF ARENE ALKENYLATION CYBB, CBR3, AHR NFE2L2 102/4885TRPA1 1407/4885HSD11B1 560/4885
US-12291593-B2 Compounds for use in catalyst compositions for the production of polyolefins RPLP0, RPS20, RPS10 NFE2L2 2039/4885TRPA1 1692/4885HSD11B1 1831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.