SCHEMBL29006191

SCHEMBL29006191

Cc1cccc([Se]CC(O)c2ccccc2)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.46
HTT P42858 2/20 0.43
MAOA P21397 1/20 0.43
LMNA P02545 2/20 0.43
ACP3 P15309 1/20 0.41
FAAH O00519 1/20 0.40
EPHX1 P07099 1/20 0.40
AOC3 Q16853 3/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
RIPK1 Q13546 1/20 0.38
GPR139 Q6DWJ6 1/20 0.37
MLKL Q8NB16 1/20 0.36
MAPT P10636 1/20 0.36
ALOX12 P18054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29006189 1.00 TAAR1 (0.46) TAAR1HTTMAOALMNAACP3
SCHEMBL29006149 0.87 LMNA (0.46) TAAR1HTTMAOALMNAAOC3
SCHEMBL29006146 0.87 LMNA (0.46) TAAR1HTTMAOALMNAAOC3
SCHEMBL29006211 0.82 MAOA (0.55) MAOALMNAAOC3KDM4EL3MBTL1
SCHEMBL29006212 0.82 MAOA (0.55) MAOALMNAAOC3KDM4EL3MBTL1
SCHEMBL29006168 0.81 CA7 (0.55) TAAR1HTTMAOALMNAAOC3
SCHEMBL29006164 0.81 CA7 (0.55) TAAR1HTTMAOALMNAAOC3
SCHEMBL29006167 0.81 MAOA (0.52) HTTMAOALMNAAOC3KDM4E
SCHEMBL29006163 0.81 MAOA (0.52) HTTMAOALMNAAOC3KDM4E
SCHEMBL29006206 0.81 LMNA (0.48) MAOALMNAACP3FAAHSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178232-A Chiral hydroxy seleno ether and asymmetric synthesis method thereof 湖北滋兰生物医药科技有限公司 2023-05-30 CN disclosed