Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29006270 | 0.87 | CNR2 (0.39) | CNR2P2RX7NTRK1LMNAGAA | |
| SCHEMBL29006246 | 0.85 | CTSA (0.38) | CTSA | |
| SCHEMBL29006291 | 0.85 | HDAC4 (0.44) | CNR2GAACTSA | |
| SCHEMBL29006263 | 0.83 | HTT (0.39) | GAAPOLBMAPK1CTSA | |
| SCHEMBL29006258 | 0.82 | HDAC3 (0.42) | GAAPOLB | |
| SCHEMBL29006269 | 0.80 | OXTR (0.41) | CNR2CYP3A4 | |
| SCHEMBL29006266 | 0.78 | KLRK1 (0.44) | LMNAACP3POLBCYP1A2CYP3A4 | |
| SCHEMBL29006262 | 0.75 | KEAP1 (0.37) | CNR2LMNAGAAPOLBCNR1 | |
| SCHEMBL29006280 | 0.75 | HDAC4 (0.41) | — | |
| SCHEMBL29006294 | 0.74 | HDAC4 (0.50) | CNR2POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003323-B | Fluorine-containing pyrazole phenylacetamide derivative and application thereof | 西北农林科技大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-116003323-A | Fluorine-containing pyrazole phenylacetamide derivative and application thereof | 西北农林科技大学 | 2023-04-25 | — | — | CN | disclosed |