Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.35 |
| ▸ | TACR3 | P29371 | 2/20 | 0.35 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29006283 | 0.88 | CTSB (0.39) | HDAC4HDAC7HDAC5MAPK1MEN1 | |
| SCHEMBL29006258 | 0.87 | HDAC3 (0.42) | HDAC4HDAC7HDAC5KMT2APOLB | |
| SCHEMBL29006279 | 0.85 | ALDH1A1 (0.43) | MAPK1ROCK1ROCK2 | |
| SCHEMBL29006266 | 0.85 | KLRK1 (0.44) | MEN1KMT2APOLB | |
| SCHEMBL29006257 | 0.85 | HDAC4 (0.46) | HDAC4HDAC7HDAC5MAPK1CNR2 | |
| SCHEMBL29006262 | 0.80 | KEAP1 (0.37) | HDAC4CNR2MEN1KMT2ACYP26A1 | |
| SCHEMBL29006291 | 0.78 | HDAC4 (0.44) | HDAC4HDAC7HDAC5CNR2 | |
| SCHEMBL29006269 | 0.77 | OXTR (0.41) | CNR2 | |
| SCHEMBL29006287 | 0.77 | CNR2 (0.40) | CNR2KMT2A | |
| SCHEMBL29006246 | 0.76 | CTSA (0.38) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003323-B | Fluorine-containing pyrazole phenylacetamide derivative and application thereof | 西北农林科技大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-116003323-A | Fluorine-containing pyrazole phenylacetamide derivative and application thereof | 西北农林科技大学 | 2023-04-25 | — | — | CN | disclosed |