Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 15/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29006246 | 0.88 | CTSA (0.38) | HDAC4CTSA | |
| SCHEMBL29006263 | 0.85 | HTT (0.39) | GAACTSA | |
| SCHEMBL29006261 | 0.85 | CNR2 (0.41) | GAACNR2CTSA | |
| SCHEMBL29006258 | 0.84 | HDAC3 (0.42) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL29006280 | 0.84 | HDAC4 (0.41) | HDAC4HDAC3HDAC7HDAC8HDAC6 | |
| SCHEMBL29006294 | 0.78 | HDAC4 (0.50) | HDAC4HDAC7HDAC5CNR2 | |
| SCHEMBL29006262 | 0.77 | KEAP1 (0.37) | HDAC4GAACNR2 | |
| SCHEMBL29006283 | 0.76 | CTSB (0.39) | HDAC4HDAC7HDAC5CTSA | |
| SCHEMBL29006269 | 0.74 | OXTR (0.41) | CNR2 | |
| SCHEMBL29006287 | 0.74 | CNR2 (0.40) | GAACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003323-B | Fluorine-containing pyrazole phenylacetamide derivative and application thereof | 西北农林科技大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-116003323-A | Fluorine-containing pyrazole phenylacetamide derivative and application thereof | 西北农林科技大学 | 2023-04-25 | — | — | CN | disclosed |