Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29006270 | 0.86 | CNR2 (0.39) | POLBNPSR1 | |
| SCHEMBL29006280 | 0.86 | HDAC4 (0.41) | MEN1KMT2A | |
| SCHEMBL29006263 | 0.85 | HTT (0.39) | HTTPOLBL3MBTL1NPSR1ALDH1A1 | |
| SCHEMBL29006260 | 0.80 | CNR1 (0.39) | HTTNPSR1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29006264 | 0.79 | TDP1 (0.40) | HTTPOLBNPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29006282 | 0.78 | HDAC3 (0.41) | POLBSMN1; SMN2TDP1 | |
| SCHEMBL29006256 | 0.75 | OXTR (0.41) | NPSR1MEN1KMT2A | |
| SCHEMBL29006257 | 0.74 | HDAC4 (0.46) | POLBNPSR1MEN1KMT2A | |
| SCHEMBL29006259 | 0.74 | NPSR1 (0.44) | POLBL3MBTL1NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29006261 | 0.73 | CNR2 (0.41) | POLBCTSATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003323-B | Fluorine-containing pyrazole phenylacetamide derivative and application thereof | 西北农林科技大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-116003323-A | Fluorine-containing pyrazole phenylacetamide derivative and application thereof | 西北农林科技大学 | 2023-04-25 | — | — | CN | disclosed |