Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.47 |
| ▸ | CCND1 | P24385 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29007170 | 0.82 | GPR84 (0.57) | CDK4CCND1MEN1KMT2AKDM4E | |
| SCHEMBL29617407 | 0.80 | CDK4 (0.43) | CDK4CCND1MEN1KMT2ALMNA | |
| SCHEMBL29617416 | 0.80 | TRPM8 (0.50) | CDK4CCND1MEN1KMT2ALMNA | |
| SCHEMBL29007184 | 0.78 | CDK4 (0.57) | CDK4CCND1MEN1KMT2ALMNA | |
| SCHEMBL29007180 | 0.76 | CDK4 (0.62) | CDK4CCND1MEN1KMT2ALMNA | |
| SCHEMBL5429887 | 0.75 | CDK4 (0.54) | CDK4CCND1MEN1KMT2ALMNA | |
| SCHEMBL5423911 | 0.73 | GPR84 (0.59) | CDK4CCND1KDM4EMAPTCYP1A2 | |
| SCHEMBL30888861 | 0.69 | CYP1A2 (0.72) | MEN1KMT2AKDM4EMAPTCYP1A2 | |
| SCHEMBL27195479 | 0.69 | CYP1A2 (0.72) | MEN1KMT2AKDM4EMAPTCYP1A2 | |
| SCHEMBL29107192 | 0.68 | KMT2A (0.45) | MEN1KMT2AMAPTTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634438-B | Preparation method of bisindolyl methane and derivative thereof | 兰州大学 | 2023-05-26 | — | — | CN | disclosed |