Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CDK4 | P11802 | 1/20 | 0.50 |
| ▸ | CCND1 | P24385 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 4/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.49 |
| ▸ | HTR1D | P28221 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29007170 | 0.85 | GPR84 (0.57) | KDM4ECDK4CCND1MAPTMEN1 | |
| SCHEMBL3193186 | 0.81 | MAPK14 (0.61) | MEN1KMT2AHSP90AA1ROCK1NPC1 | |
| SCHEMBL29007184 | 0.80 | CDK4 (0.57) | KDM4ECDK4CCND1MAPTMEN1 | |
| SCHEMBL29007166 | 0.80 | CDK4 (0.47) | KDM4ECDK4CCND1MAPTMEN1 | |
| SCHEMBL6098412 | 0.78 | PPARD (0.49) | MEN1KMT2APTPN1ROCK1NPC1 | |
| SCHEMBL29007180 | 0.78 | CDK4 (0.62) | KDM4ECDK4CCND1MAPTMEN1 | |
| SCHEMBL5429887 | 0.77 | CDK4 (0.54) | KDM4ECDK4CCND1MAPTMEN1 | |
| SCHEMBL5423911 | 0.76 | GPR84 (0.59) | TRPM8KDM4ECDK4CCND1MAPT | |
| SCHEMBL6086123 | 0.76 | MAPK14 (0.54) | MEN1KMT2AHSP90AA1ROCK1NPC1 | |
| SCHEMBL6100496 | 0.76 | ALOX5 (0.61) | MAPTMEN1KMT2AROCK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634438-A | Preparation method of diindolylmethane and derivatives thereof | 兰州大学 | 2022-06-17 | — | — | CN | disclosed |