Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.57 |
| ▸ | CDK4 | P11802 | 3/20 | 0.55 |
| ▸ | CCND1 | P24385 | 3/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423911 | 0.90 | GPR84 (0.59) | GPR84CDK4CCND1HTR1AKDM4E | |
| SCHEMBL29617416 | 0.85 | TRPM8 (0.50) | CDK4CCND1KMT2AMEN1KDM4E | |
| SCHEMBL29007180 | 0.85 | CDK4 (0.62) | GPR84CDK4CCND1KMT2AMEN1 | |
| SCHEMBL29007166 | 0.82 | CDK4 (0.47) | GPR84CDK4CCND1KMT2AMEN1 | |
| SCHEMBL29007184 | 0.82 | CDK4 (0.57) | GPR84CDK4CCND1KMT2AMEN1 | |
| SCHEMBL5429887 | 0.82 | CDK4 (0.54) | GPR84CDK4CCND1KMT2AMEN1 | |
| SCHEMBL29617407 | 0.77 | CDK4 (0.43) | CDK4CCND1KMT2AMEN1DRD2 | |
| SCHEMBL29073981 | 0.77 | HTR2C (0.52) | KMT2AMEN1KDM4EHTR2CMAPT | |
| SCHEMBL28481231 | 0.76 | HTR2C (0.51) | HTR2C | |
| SCHEMBL2156618 | 0.74 | HTR2C (0.56) | ALDH1A1HTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114634438-B | Preparation method of bisindolyl methane and derivative thereof | 兰州大学 | 2023-05-26 | — | — | CN | disclosed |
| CN-114634438-A | Preparation method of diindolylmethane and derivatives thereof | 兰州大学 | 2022-06-17 | — | — | CN | disclosed |