SCHEMBL29007684

SCHEMBL29007684

Cc1ccccc1CC(NC(=O)C(C)(C)C)C(=O)OC(=O)CN

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 3/20 0.38
NLRP3 Q96P20 1/20 0.35
POLB P06746 1/20 0.34
MAPK1 P28482 1/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
LMNA P02545 2/20 0.34
TSHR P16473 1/20 0.34
TACR1 P25103 1/20 0.34
ACE P12821 1/20 0.33
GRIA1 P42261 1/20 0.33
ATM Q13315 1/20 0.33
KMT2A Q03164 1/20 0.33
EPHX2 P34913 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28883299 0.85 OPRK1 (0.49) OPRK1NLRP3POLBLMNAATM
SCHEMBL19355121 0.70 OPRK1 (0.52) OPRK1NLRP3POLBTACR1ATM
SCHEMBL28883458 0.69 SCN9A (0.48) OPRK1POLBMAPK1PPARGPPARA
SCHEMBL23170061 0.68 CTSG (0.53) POLBTACR1ATM
SCHEMBL32676964 0.68 OPRK1 (0.50) OPRK1NLRP3POLBTSHRATM
SCHEMBL32676961 0.68 OPRK1 (0.50) OPRK1NLRP3POLBTSHRATM
SCHEMBL32676897 0.68 OPRK1 (0.50) OPRK1NLRP3POLBTSHRATM
SCHEMBL16458598 0.68 CTSS (0.48) MAPK1PPARGPPARALMNATACR1
SCHEMBL16458597 0.68 CTSS (0.48) MAPK1PPARGPPARALMNATACR1
SCHEMBL11940456 0.67 ATM (0.63) POLBLMNAATMKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178486-A Asymmetric hydrogenation synthesis method and application of non-natural polypeptide 西南大学 2023-05-30 CN disclosed