Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL19207401 | 0.81 | — | — | |
| Propylene Glycol SCHEMBL29058943 | 0.81 | — | — | |
| Propylene Glycol SCHEMBL28118329 | 0.79 | TDP1 (0.62) | TDP1TSHRCA2LMNA | |
| Propylene Glycol SCHEMBL11598351 | 0.77 | — | — | |
| Propylene Glycol SCHEMBL6891171 | 0.77 | — | — | |
| Propylene Glycol SCHEMBL27550189 | 0.77 | TDP1 (0.83) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL7522896 | 0.77 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL28578 | 0.77 | — | — | |
| Propylene Glycol SCHEMBL724028 | 0.77 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNA | |
| Propylene Glycol SCHEMBL161401 | 0.77 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778493-B | Polypropylene carbonate polyol type water-based polyurethane waterproof emulsion and preparation method and application thereof | 惠州大亚湾达志精细化工有限公司 | 2023-04-28 | — | — | CN | disclosed |