SCHEMBL809243

SCHEMBL809243

CCC(CC)(C(=O)OC)C(=O)OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.40
TSHR P16473 5/20 0.38
ALDH1A1 P00352 3/20 0.37
POLB P06746 1/20 0.37
PTPRB P23467 2/20 0.36
KCNN4 O15554 1/20 0.36
MGAM O43451 2/20 0.35
GAA P10253 2/20 0.35
SI P14410 2/20 0.35
MGAM2 Q2M2H8 2/20 0.35
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
PTPN1 P18031 2/20 0.33
TET2 Q6N021 1/20 0.33
PTPN2 P17706 1/20 0.33
PTPRA P18433 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29674742 0.97 DGAT1 (0.39) DGAT1TSHRALDH1A1POLBPTPRB
SCHEMBL29008744 0.87 MEN1 (0.48) TSHRALDH1A1PTPRBMGAMGAA
SCHEMBL4901424 0.86 ALDH1A1 (0.38) DGAT1TSHRALDH1A1POLBPTPRB
SCHEMBL221073 0.86 PTPN1 (0.40) DGAT1TSHRALDH1A1POLBPTPRB
SCHEMBL17617136 0.85 ALDH1A1 (0.39) DGAT1TSHRALDH1A1POLBPTPRB
SCHEMBL16661305 0.85 DGAT1 (0.58) DGAT1TSHRALDH1A1POLBPTPRB
SCHEMBL11733392 0.84 DGAT1 (0.34) DGAT1TSHRALDH1A1POLBPTPRB
SCHEMBL18346585 0.84 ALDH1A1 (0.37) DGAT1TSHRALDH1A1POLBPTPRB
SCHEMBL10371056 0.84 DGAT1 (0.34) DGAT1TSHRALDH1A1POLBPTPRB
SCHEMBL29008751 0.83 HCAR2 (0.36) TSHRALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114605622-B Aliphatic polyester with malonic acid structure, and preparation method and application thereof 苏州瀚海新材料有限公司 2024-04-02 CN claimed
CN-117700654-A Copolyester for weather-resistant coating and preparation method and application thereof 中瀚新材料科技有限公司 2024-03-15 CN claimed
CN-114605622-A Aliphatic polyester with malonic acid structure and preparation method and application thereof 苏州瀚海新材料有限公司 2022-06-10 CN claimed
CN-108383998-B A kind of high intensity humidity response polyhydroxyamide and preparation method thereof 安徽农业大学 2019-10-08 CN claimed
CN-108383998-A A kind of high intensity humidity response polyhydroxyamide and preparation method thereof 安徽农业大学 2018-08-10 CN claimed
US-20080182767-A1 Compounds and Lubricating Compositions Containing the Compounds AFTON CHEMICAL CORPORATION 2008-07-31 US claimed
US-6415614-B1 CONTROLLING VAPOR PRESSURE OF MIXTURE VISTEON GLOBAL TECHNOLOGIES, INC. 2002-07-09 US claimed
EP-0674233-B1 Recording sheets XEROX CORP (US) 2000-05-24 EP claimed
US-6045950-A A LITHIUM BATTERY CONTAINING AN ELECTROLYTE CONTAINING A MALONATE ESTER HAVING NO ALPHA-CARBON HYDROGEN ATOMS; A CATHODE THAT BECOMES LITHIATED DURING DISCHARGE OF LITHIUM BATTERY, AN ANODE AND A SEPARATOR BETWEEN ANODE AND CATHODE DURACELL INC. (US) 2000-04-04 US claimed
US-6025487-A Isomerisation process GLAXO WELLCOME SPA (IT) 2000-02-15 US claimed
WO-2000001027-A1 SOLVENT FOR ELECTROLYTIC SOLUTIONS DURACELL INC. (US) 2000-01-06 WO claimed
US-5928765-A Recording sheets XEROX CORPORATION (US) 1999-07-27 US claimed
EP-0871635-A1 ISOMERISATION PROCESS GLAXO WELLCOME S.p.A. (IT) 1998-10-21 EP claimed
WO-1997006174-A1 ISOMERISATION PROCESS GLAXO WELLCOME SPA (IT) 1997-02-20 WO claimed
EP-0674233-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
US-12637680-B2 Recombinant host cells for the production of malonate LYGOS, INC. (US) 2026-05-26 US disclosed
CN-119709450-A Recombinant host cells for malonate production 利戈斯股份有限公司 2025-03-28 CN disclosed
US-4232131-A POLYAMIDE CIBA-GEIGY CORPORATION (US) 1980-11-04 US disclosed
US-3997682-A Oleaginous food flavored with certain alpha carboxy acids and/or esters thereof ANDERSON, CLAYTON & CO. (US) 1976-12-14 US disclosed
US-3932121-A Process for the dyeing of modified polyester fibers HODOGAYA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637680-B2 Recombinant host cells for the production of malonate DCXR, ETV1, LYPLA2 DGAT1 387/4885TSHR 1351/4885ALDH1A1 1554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.