SCHEMBL29009128

SCHEMBL29009128

c1ccc(-c2cnn(C3CCCC3)n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.45
DAGLA Q9Y4D2 1/20 0.42
HPGD P15428 1/20 0.40
NPC1 O15118 3/20 0.38
RAB9A P51151 3/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
IL4I1 Q96RQ9 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
RAD52 P43351 1/20 0.36
ALDH1A1 P00352 1/20 0.36
WDR5 P61964 1/20 0.36
SRC P12931 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10040497 0.85 CHRNB2 (0.48) HCRTR1KMT2AMEN1ALDH1A1
SCHEMBL28570675 0.76 ALOX15 (0.39) HCRTR1DAGLAHPGDNPC1RAB9A
SCHEMBL22290686 0.74 IDO1 (0.43) HCRTR1HPGDNPC1RAB9AKMT2A
SCHEMBL10040513 0.73 GPR119 (0.51) KMT2AMEN1SRC
SCHEMBL20899673 0.72 HCRTR1 (0.38) HCRTR1DAGLAKMT2AMEN1SMN1; SMN2
SCHEMBL29152983 0.69 KMT2A (0.47) HPGDNPC1RAB9ACNR1CNR2
SCHEMBL5288314 0.69 CNR1 (0.52) HPGDNPC1RAB9ACNR1CNR2
SCHEMBL5288319 0.69 HPGD (0.54) HPGDNPC1RAB9ACNR1CNR2
SCHEMBL20816392 0.68 DRD2 (0.63) HPGDNPC1RAB9AKMT2AMEN1
SCHEMBL21149896 0.67 TSHR (0.37) HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178286-B N (N)2Alkyl substituted triazole derivative and synthetic method and application thereof 华东师范大学 2024-12-03 CN disclosed
CN-116178286-A High-selectivity N 2 Alkyl substituted triazole derivative and synthetic method and application thereof 华东师范大学 2023-05-30 CN disclosed