Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009183 | 0.89 | ALOX15 (0.48) | ALOX15SMN1; SMN2GAACA1CA2 | |
| SCHEMBL29009151 | 0.87 | ALDH1A1 (0.45) | RXFP1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL29009185 | 0.71 | ALDH1A1 (0.50) | GAACA1CA2KMT2AALDH1A1 | |
| SCHEMBL14987372 | 0.70 | TSHR (0.75) | SMN1; SMN2GAACA1CA2POLB | |
| SCHEMBL12259135 | 0.68 | SMN1; SMN2 (0.60) | ALOX15SMN1; SMN2RXFP1CCR1L3MBTL1 | |
| SCHEMBL29009201 | 0.67 | ALDH1A1 (0.49) | GAACA1CA2KMT2AALDH1A1 | |
| SCHEMBL29009197 | 0.66 | CHRNA7 (0.52) | ALOX15SMN1; SMN2KMT2AOPRK1 | |
| SCHEMBL13727000 | 0.65 | CA1 (0.41) | SMN1; SMN2CA1CA2POLBL3MBTL1 | |
| SCHEMBL11817128 | 0.65 | KDM4E (0.76) | SMN1; SMN2GAAPOLBKMT2AALDH1A1 | |
| SCHEMBL19112883 | 0.64 | POLB (0.56) | SMN1; SMN2CA1CA2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |