Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009167 | 0.87 | ALOX15 (0.50) | ALDH1A1KDM4ERXFP1MEN1KMT2A | |
| SCHEMBL29009183 | 0.79 | ALOX15 (0.48) | ALDH1A1KDM4ERXFP1MEN1KMT2A | |
| SCHEMBL29009191 | 0.74 | RXFP1 (0.47) | ALDH1A1KDM4EHPGDTDP1RXFP1 | |
| SCHEMBL29009154 | 0.71 | GAA (0.42) | ALDH1A1KDM4ETDP1RXFP1MEN1 | |
| SCHEMBL2569399 | 0.70 | NPSR1 (0.49) | ALDH1A1KDM4EHPGDTDP1MEN1 | |
| SCHEMBL14986928 | 0.69 | TSHR (0.75) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL29009203 | 0.66 | MEN1 (0.43) | ALDH1A1KDM4ETDP1RXFP1MEN1 | |
| SCHEMBL29009150 | 0.65 | SLC6A3 (0.46) | SLC6A3SLC6A4OPRK1SLC6A2 | |
| SCHEMBL8441842 | 0.65 | TSHR (0.68) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL13960054 | 0.65 | TP53 (0.45) | ALDH1A1KDM4ELMNASLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |