Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29009151 | 0.74 | ALDH1A1 (0.45) | RXFP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6521371 | 0.73 | KMT2A (0.41) | RXFP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29009183 | 0.72 | ALOX15 (0.48) | RXFP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1225830 | 0.69 | RXFP1 (0.40) | RXFP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9103921 | 0.69 | RXFP1 (0.40) | RXFP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL28642735 | 0.67 | KDM4E (0.46) | RXFP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16178557 | 0.65 | TSHR (0.50) | RXFP1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1225559 | 0.63 | P2RX7 (0.50) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL1225931 | 0.63 | P2RX7 (0.50) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL13254951 | 0.62 | MEN1 (0.34) | RXFP1MEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217458-A | 2-carbonyl-5-phenylpyrrole compound, preparation method, application and derivative thereof, and pharmaceutical composition | 湖北民族大学 | 2023-06-06 | — | — | CN | disclosed |