Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.49 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27594834 | 0.81 | HPGD (0.65) | HPGDRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL8573730 | 0.77 | HPGD (0.65) | HPGDRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL31151793 | 0.77 | HPGD (0.65) | HPGDRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL29009650 | 0.76 | PLAU (0.49) | HPGDRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL31276830 | 0.75 | RAB9A (0.46) | HPGDRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12988856 | 0.73 | GABRA1 (0.72) | HPGDRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL109220 | 0.73 | HPGD (0.70) | HPGDRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL29009680 | 0.73 | HPGD (0.50) | HPGDRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL30128152 | 0.72 | HPGD (0.54) | HPGDRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL14309148 | 0.72 | HPGD (0.58) | HPGDRAB9ANPC1ALDH1A1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010564-B | Preparation method of o-iodophenyl compound | 苏州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-115010564-A | Preparation method of o-iodophenyl compound | 苏州大学 | 2022-09-06 | — | — | CN | disclosed |