SCHEMBL29010044

SCHEMBL29010044

O=C(O)C(CC(F)F)(c1ccccc1)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
PTPN1 P18031 1/20 0.37
CYP2D6 P10635 1/20 0.37
CHRM1 P11229 3/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
ALDH1A1 P00352 4/20 0.36
TSHR P16473 2/20 0.36
S1PR4 O95977 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
S1PR1 P21453 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
HIF1A Q16665 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
CES1 P23141 2/20 0.35
CYP2C19 P33261 1/20 0.35
KIF11 P52732 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12837474 0.79 CYP1A2 (0.42) CYP1A2PTPN1CYP2D6CHRM1CHRM4
SCHEMBL4551817 0.78 CYP1A2 (0.41) CYP1A2PTPN1CYP2D6CHRM1CHRM4
SCHEMBL3261996 0.75 CYP1A2 (0.42) CYP1A2PTPN1CYP2D6CHRM1CHRM4
SCHEMBL19812943 0.70 ALDH1A1 (0.46) CYP1A2CYP2D6CHRM1ALDH1A1TSHR
SCHEMBL1843172 0.70 KIF11 (0.43) CYP1A2CYP2D6ALDH1A1S1PR4LMNA
SCHEMBL19812940 0.69 CYP2C19 (0.44) CYP1A2PTPN1CYP2D6CHRM1CHRM4
SCHEMBL29010065 0.68 CYP1A2 (0.42) CYP1A2PTPN1CYP2D6ALDH1A1TSHR
SCHEMBL2699401 0.68 MAPT (0.48) PTPN1CYP2D6CHRM1ALDH1A1LMNA
SCHEMBL28147722 0.67 CYP1A2 (0.45) CYP1A2PTPN1CYP2D6ALDH1A1TSHR
SCHEMBL27528437 0.67 CES1 (0.50) PTPN1ALDH1A1TSHRS1PR4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed