Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | ALDH3A1 | P30838 | 6/20 | 0.63 |
| ▸ | ALDH2 | P05091 | 4/20 | 0.63 |
| ▸ | ACHE | P22303 | 3/20 | 0.61 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.58 |
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147994 | 0.95 | ALDH1A1 (0.62) | ALDH1A1ALDH3A1ALDH2ACHECUL4A | |
| SCHEMBL29011247 | 0.94 | ALDH1A1 (0.60) | ALDH1A1ALDH3A1ALDH2ACHECUL4A | |
| SCHEMBL29220077 | 0.90 | ALDH1A1 (0.67) | ALDH1A1ALDH3A1ALDH2ACHECUL4A | |
| SCHEMBL28606638 | 0.84 | CES1 (0.65) | ALDH1A1ALDH3A1ALDH2ACHECUL4A | |
| SCHEMBL29011260 | 0.83 | ALDH3A1 (0.62) | ALDH1A1ALDH3A1ALDH2CES1BCHE | |
| SCHEMBL16045157 | 0.83 | ALDH1A1 (0.67) | ALDH1A1ACHECES1BCHEMEN1 | |
| SCHEMBL21001752 | 0.83 | ALDH1A1 (0.65) | ALDH1A1ALDH3A1ALDH2ACHECUL4A | |
| SCHEMBL22667351 | 0.82 | ALDH1A1 (0.58) | ALDH1A1ALDH3A1ALDH2ACHECUL4A | |
| SCHEMBL30404925 | 0.82 | ALDH1A1 (0.58) | ALDH1A1ALDH3A1ALDH2ACHECUL4A | |
| SCHEMBL29011262 | 0.80 | PARK7 (0.64) | ALDH1A1CES1BCHEMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119735585-A | Novel substituted isatin-coumarin derivative and preparation method and application thereof | 广东医科大学 | 2025-04-01 | — | — | CN | disclosed |
| CN-118108654-B | Substituted isatin-ferulic acid ester derivative and preparation method and application thereof | 广东医科大学 | 2025-03-07 | — | — | CN | disclosed |
| CN-116217547-B | Substituted isatin-8-hydroxyquinoline derivative and preparation method and application thereof | 广东医科大学 | 2024-10-22 | — | — | CN | disclosed |
| CN-118108654-A | Substituted isatin-ferulic acid ester derivative and preparation method and application thereof | 广东医科大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-116217547-A | Substituted isatin-8-hydroxyquinoline derivative and preparation method and application thereof | 广东医科大学 | 2023-06-06 | — | — | CN | disclosed |