Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29011609 | 0.87 | FFAR4 (0.54) | FFAR4HTTMAPTMEN1KMT2A | |
| SCHEMBL29011616 | 0.85 | FFAR4 (0.49) | FFAR4HTTMAPTMEN1KMT2A | |
| SCHEMBL29011594 | 0.85 | FFAR4 (0.49) | FFAR4HTTMAPTMEN1KMT2A | |
| SCHEMBL9568608 | 0.84 | LMNA (0.54) | FFAR4HTTMAPTMEN1KMT2A | |
| SCHEMBL9568712 | 0.76 | TCF4 (0.58) | FFAR4MAPTMEN1KMT2ALMNA | |
| SCHEMBL5955976 | 0.76 | POLB (0.58) | FFAR4HTTMAPTMEN1KMT2A | |
| SCHEMBL7572319 | 0.76 | POLB (0.68) | HTTMAPTMEN1KMT2APOLB | |
| SCHEMBL24810564 | 0.75 | NFE2L2 (0.47) | MAPTMEN1KMT2APOLBLMNA | |
| SCHEMBL28422486 | 0.75 | KMT2A (0.43) | HTTMAPTMEN1KMT2ALMNA | |
| SCHEMBL9568785 | 0.74 | PTGDR2 (0.48) | HTTMAPTMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028581-B | Preparation method of hydrogenated phenanthridine derivative and application of hydrogenated phenanthridine derivative in preparation of antitumor drugs | 常州大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-115028581-A | Preparation method of hydrogenated phenanthridine derivatives and application of hydrogenated phenanthridine derivatives in preparation of antitumor drugs | 常州大学 | 2022-09-09 | — | — | CN | disclosed |