SCHEMBL9568608

SCHEMBL9568608

C=CC(=O)Oc1ccccc1NS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.54
TSHR P16473 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
POLB P06746 2/20 0.54
MAPT P10636 2/20 0.54
USP2 O75604 1/20 0.54
ALDH1A1 P00352 1/20 0.54
NOD2 Q9HC29 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
FFAR4 Q5NUL3 1/20 0.50
KEAP1 Q14145 1/20 0.50
NFE2L2 Q16236 1/20 0.50
CA1 P00915 1/20 0.50
CA4 P22748 1/20 0.50
CA7 P43166 1/20 0.50
HTT P42858 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568785 0.89 PTGDR2 (0.48) LMNATSHRSMN1; SMN2POLBMAPT
SCHEMBL29011602 0.84 FFAR4 (0.51) LMNATSHRSMN1; SMN2CYP2C9CYP2C19
SCHEMBL3251006 0.83 LMNA (0.59) LMNATSHRSMN1; SMN2CYP2C9CYP2C19
SCHEMBL29011609 0.82 FFAR4 (0.54) LMNATSHRSMN1; SMN2CYP2C9CYP2C19
SCHEMBL9568664 0.81 HSD17B10 (0.45) TSHRSMN1; SMN2ALDH1A1L3MBTL1KEAP1
SCHEMBL29011594 0.81 FFAR4 (0.49) LMNATSHRSMN1; SMN2CYP2C9CYP2C19
SCHEMBL29011616 0.81 FFAR4 (0.49) LMNATSHRSMN1; SMN2CYP2C9CYP2C19
SCHEMBL9568642 0.79 THRB (0.49) LMNAMAPTALDH1A1KDM4EHSD17B10
SCHEMBL9568712 0.79 TCF4 (0.58) LMNASMN1; SMN2MAPTALDH1A1CA2
SCHEMBL8752514 0.78 LMNA (0.55) LMNATSHRSMN1; SMN2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115028581-B Preparation method of hydrogenated phenanthridine derivative and application of hydrogenated phenanthridine derivative in preparation of antitumor drugs 常州大学 2024-04-30 CN disclosed
CN-115028581-A Preparation method of hydrogenated phenanthridine derivatives and application of hydrogenated phenanthridine derivatives in preparation of antitumor drugs 常州大学 2022-09-09 CN disclosed
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed